!version: $Revision: 1.1 $ !date: Fri Dec 05 10:04:14 EST 2003 !saved-by: hjd !autogenerated-by: DAG-Edit version 1.407 ! !Gene Ontology definitions ! term: 'de novo' protein folding goid: GO:0006458 definition: Processes that assist the folding of a nascent peptide chain into its correct tertiary structure. definition_reference: Sanger:mb term: (+)-borneol dehydrogenase activity goid: GO:0047500 definition: Catalysis of the reaction: (+)-borneol + NAD+ = (+)-camphor + NADH + H+. definition_reference: MetaCyc:(+)-BORNEOL-DEHYDROGENASE-RXN definition_reference: EC:1.1.1.198 term: (+)-camphor biosynthesis goid: GO:0046211 definition: The formation from simpler components of (+)-camphor, a bicyclic monoterpene ketone. definition_reference: GO:ai term: (+)-camphor catabolism goid: GO:0019383 definition: The breakdown into simpler components of (+)-camphor, a bicyclic monoterpene ketone. definition_reference: UM-BBD:pathway definition_reference: http://umbbd.ahc.umn.edu/cam/cam_map.html term: (+)-camphor metabolism goid: GO:0018882 definition: The chemical reactions and physical changes involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed. definition_reference: UM-BBD:pathway definition_reference: http://umbbd.ahc.umn.edu/cam/cam_map.html term: (+)-delta-cadinene synthase activity goid: GO:0047461 definition: Catalysis of the reaction: trans,trans-farnesyl diphosphate = pyrophosphate + (+)-delta-cadinene. definition_reference: MetaCyc:4.6.1.11-RXN definition_reference: EC:4.2.3.13 term: (+)-neomenthol dehydrogenase activity goid: GO:0047501 definition: Catalysis of the reaction: (+)-neomenthol + NADP+ = (-)-menthone + NADPH + H+. definition_reference: MetaCyc:(+)-NEOMENTHOL-DEHYDROGENASE-RXN definition_reference: EC:1.1.1.208 term: (+)-sabinol dehydrogenase activity goid: GO:0047502 definition: Catalysis of the reaction: (+)-cis-sabinol + NAD+ = (+)-sabinone + NADH + H+. definition_reference: MetaCyc:(+)-SABINOL-DEHYDROGENASE-RXN definition_reference: EC:1.1.1.228 term: (-)-(4S)-limonene synthase activity goid: GO:0050552 definition: Catalysis of the reaction: geranyl diphosphate = limonene + diphosphate. definition_reference: MetaCyc:4.2.3.16-RXN definition_reference: EC:4.2.3.16 term: (-)-borneol dehydrogenase activity goid: GO:0047503 definition: Catalysis of the reaction: (-)-borneol + NAD+ = (-)-camphor + NADH + H+. definition_reference: MetaCyc:(-)-BORNEOL-DEHYDROGENASE-RXN definition_reference: EC:1.1.1.227 term: (-)-endo-fenchol synthase activity goid: GO:0050437 definition: Catalysis of the reaction: H2O + geranyl-PP = pyrophosphate + (-)-endo-fenchol. definition_reference: MetaCyc:4.2.3.10-RXN definition_reference: EC:4.2.3.10 term: (-)-limonene 3-monooxygenase activity goid: GO:0018674 definition: Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-isopiperitenol + NADP+ + H2O. definition_reference: EC:1.14.13.47 term: (-)-limonene 6-monooxygenase activity goid: GO:0018675 definition: Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O. definition_reference: EC:1.14.13.48 term: (-)-limonene 7-monooxygenase activity goid: GO:0018676 definition: Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-perillyl alcohol + NADP+ + H2O. definition_reference: EC:1.14.13.49 term: (-)-menthol dehydrogenase activity goid: GO:0047504 definition: Catalysis of the reaction: (-)-menthol + NADP+ = (-)-menthone + NADPH + H+. definition_reference: MetaCyc:(-)-MENTHOL-DEHYDROGENASE-RXN definition_reference: EC:1.1.1.207 term: (-)-menthol monooxygenase activity goid: GO:0047505 definition: Catalysis of the reaction: (-)-menthol + NADPH + H+ + O2 = p-menthane-3,8-diol + NADP+ + H2O. definition_reference: MetaCyc:(-)-MENTHOL-MONOOXYGENASE-RXN definition_reference: EC:1.14.13.46 term: (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity goid: GO:0047470 definition: Catalysis of the reaction: 4-(1,4-alpha-D-glucosyl)(n-1)-D-glucose = 1-alpha-D-(1,4-alpha-D-glucosyl)(n-1)-alpha-D-glucopyranoside. definition_reference: MetaCyc:5.4.99.15-RXN definition_reference: EC:5.4.99.15 term: (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity goid: GO:0047446 definition: Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = cyclohexanone + acetyl-CoA. definition_reference: MetaCyc:4.1.3.35-RXN definition_reference: EC:4.1.3.35 term: (2,3-dihydroxybenzoyl)adenylate synthase activity goid: GO:0008668 definition: Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate = diphosphate + (2,3-dihydroxybenzoyl)adenylate. definition_reference: EC:2.7.7.58 definition_reference: MetaCyc:2.7.7.58-RXN term: (3,5-dichlorophenylurea)acetate amidohydrolase activity goid: GO:0018749 definition: Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine. definition_reference: UM-BBD_enzymeID:e0440 term: (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthesis from asparagine goid: GO:0046550 definition: The modification of asparagine to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine as found in microcin C7 produced from the mccA gene in E. coli plasmid pMccC7. definition_reference: RESID:AA0328 definition_reference: PMID:8183363 definition_reference: PMID:7559516 term: (3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase activity goid: GO:0008659 definition: Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O. definition_reference: EC:4.2.1.- definition_reference: GO:ai term: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity goid: GO:0047120 definition: Catalysis of the reaction: NAD+ + (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate = NADH + CO2 + protocatechuate. definition_reference: MetaCyc:1.3.1.53-RXN definition_reference: EC:1.3.1.53 term: (alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3)-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity goid: GO:0047290 definition: Catalysis of the reaction: alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(alpha-N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl-R + CMP. definition_reference: MetaCyc:2.4.99.7-RXN definition_reference: EC:2.4.99.7 term: (delayed) early viral mRNA transcription goid: GO:0019084 definition: The second round of viral gene transcription; most genes transcribed in this round are necessary for genome replication. definition_reference: ISBN:0781702534 term: (deoxy)adenylate kinase activity goid: GO:0047506 definition: Catalysis of the reaction: ATP + dAMP = ADP + dADP. definition_reference: MetaCyc:(DEOXY)ADENYLATE-KINASE-RXN definition_reference: EC:2.7.4.11 term: (deoxy)nucleoside-phosphate kinase activity goid: GO:0047507 definition: Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate. definition_reference: MetaCyc:(DEOXY)NUCLEOSIDE-PHOSPHATE-KINASE-RXN definition_reference: EC:2.7.4.13 term: (iso)eugenol O-methyltransferase activity goid: GO:0050630 definition: Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol. definition_reference: MetaCyc:2.1.1.146-RXN definition_reference: EC:2.1.1.146 term: (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity goid: GO:0003947 definition: Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide. definition_reference: EC:2.4.1.92 term: (R)-2-hydroxy-fatty-acid dehydrogenase activity goid: GO:0047049 definition: Catalysis of the reaction: NAD+ + R-2-hydroxystearate = NADH + 2-oxostearate. definition_reference: MetaCyc:1.1.1.98-RXN definition_reference: EC:1.1.1.98 term: (R)-2-hydroxyacid dehydrogenase activity goid: GO:0050578 definition: Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+. definition_reference: MetaCyc:1.1.1.272-RXN definition_reference: EC:1.1.1.272 term: (R)-2-methylmalate dehydratase activity goid: GO:0047508 definition: Catalysis of the reaction: (R)-2-methylmalate = 2-methylmaleate + H2O. definition_reference: MetaCyc:(R)-2-METHYLMALATE-DEHYDRATASE-RXN definition_reference: EC:4.2.1.35 term: (R)-3-amino-2-methylpropionate transaminase activity goid: GO:0047314 definition: Catalysis of the reaction: 2-oxoglutarate + (R)-3-amino-2-methylpropanoate = L-glutamate + methylmalonate-semialdehyde. definition_reference: MetaCyc:2.6.1.61-RXN definition_reference: EC:2.6.1.61 term: (R)-3-amino-2-methylpropionate-pyruvate transaminase activity goid: GO:0047305 definition: Catalysis of the reaction: pyruvate + (R)-3-amino-2-methylpropanoate = L-alanine + methylmalonate-semialdehyde. definition_reference: MetaCyc:2.6.1.40-RXN definition_reference: EC:2.6.1.40 term: (R)-3-hydroxyacid ester dehydrogenase activity goid: GO:0047108 definition: Catalysis of the reaction: NADP+ + ethyl (R)-3-hydroxyhexanoate = NADPH + ethyl-3-oxohexanoate. definition_reference: MetaCyc:1.2.1.55-RXN definition_reference: EC:1.2.1.55 term: (R)-4-hydroxymandelate catabolism goid: GO:0019599 definition: The breakdown into simpler components of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid. definition_reference: GO:ai term: (R)-4-hydroxymandelate metabolism goid: GO:0046431 definition: The chemical reactions and physical changes involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate). definition_reference: ISBN:0198506732 definition_reference: GO:ai term: (R)-4-hydroxyphenyllactate dehydrogenase activity goid: GO:0047029 definition: Catalysis of the reaction: NAD(P)+ + (R)-3-(4-hydroxyphenyl)lactate = NAD(P)H + 3-(4-hydroxyphenyl)pyruvate. definition_reference: MetaCyc:1.1.1.222-RXN definition_reference: EC:1.1.1.222 term: (R)-6-hydroxynicotine oxidase activity goid: GO:0018530 definition: Catalysis of the reaction: (R)-6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + H2O2. definition_reference: EC:1.5.3.6 term: (R)-aminopropanol dehydrogenase activity goid: GO:0019147 definition: Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD+ = aminoacetone + NADH + H+. definition_reference: EC:1.1.1.75 term: (R)-dehydropantoate dehydrogenase activity goid: GO:0047509 definition: Catalysis of the reaction: (R)-4-dehydropantoate + NAD+ + H2O = (R)-3,3-dimethylmalate + NADH + H+. definition_reference: MetaCyc:(R)-DEHYDROPANTOATE-DEHYDROGENASE-RXN definition_reference: EC:1.2.1.33 term: (R)-mandelate catabolism to benzoate goid: GO:0019597 definition: The breakdown of (R)-mandelate into simpler components, including benzoate. definition_reference: GO:curators term: (R)-mandelate catabolism to catechol goid: GO:0019598 definition: The breakdown of (R)-mandelate into simpler components, including catechol. definition_reference: GO:curators term: (R)-pantolactone dehydrogenase (flavin) activity goid: GO:0047060 definition: Catalysis of the reaction: acceptor + pantoyl lactone = reduced acceptor + 2-dehydropantoyl lactone. definition_reference: MetaCyc:1.1.99.27-RXN definition_reference: EC:1.1.99.27 term: (R,R)-butanediol dehydrogenase activity goid: GO:0000721 definition: Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+. definition_reference: EC:1.1.1.4 term: (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity goid: GO:0030776 definition: Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline. definition_reference: EC:2.1.1.115 term: (RS)-norcoclaurine 6-O-methyltransferase activity goid: GO:0030786 definition: Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine. definition_reference: EC:2.1.1.128 term: (S)-2-hydroxy-acid oxidase activity goid: GO:0003973 definition: Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + H2O2. definition_reference: EC:1.1.3.15 term: (S)-2-hydroxy-fatty-acid dehydrogenase activity goid: GO:0047050 definition: Catalysis of the reaction: NAD+ + (S)-2-hydroxystearate = NADH + 2-oxostearate. definition_reference: MetaCyc:1.1.1.99-RXN definition_reference: EC:1.1.1.99 term: (S)-2-methylmalate dehydratase activity goid: GO:0047510 definition: Catalysis of the reaction: (S)-2-methylmalate = 2-methylfumarate + H2O. definition_reference: MetaCyc:(S)-2-METHYLMALATE-DEHYDRATASE-RXN definition_reference: EC:4.2.1.34 term: (S)-3-amino-2-methylpropionate transaminase activity goid: GO:0047298 definition: Catalysis of the reaction: 2-oxoglutarate + (S)-3-amino-2-methylpropanoate = L-glutamate + methylmalonate-semialdehyde. definition_reference: MetaCyc:2.6.1.22-RXN definition_reference: EC:2.6.1.22 term: (S)-3-hydroxyacid ester dehydrogenase activity goid: GO:0047109 definition: Catalysis of the reaction: NADP+ + ethyl (S)-3-hydroxyhexanoate = NADPH + ethyl-3-oxohexanoate. definition_reference: MetaCyc:1.2.1.56-RXN definition_reference: EC:1.2.1.56 term: (S)-6-hydroxynicotine oxidase activity goid: GO:0018531 definition: Catalysis of the reaction: (S)-6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + H2O2. definition_reference: EC:1.5.3.5 term: (S)-canadine synthase activity goid: GO:0047056 definition: Catalysis of the reaction: O2 + NADPH + S-tetrahydrocolumbamine = 2 H2O + NADP+ + S-canadine. definition_reference: MetaCyc:1.1.3.36-RXN definition_reference: EC:1.14.21.5 term: (S)-carnitine 3-dehydrogenase activity goid: GO:0047041 definition: Catalysis of the reaction: NAD+ + L-carnitine = NADH + 3-dehydrocarnitine. definition_reference: MetaCyc:1.1.1.254-RXN definition_reference: EC:1.1.1.254 term: (S)-cheilanthifoline synthase activity goid: GO:0047053 definition: Catalysis of the reaction: O2 + NADPH + S-scoulerine = 2 H2O + NADP+ + S-cheilanthifoline. definition_reference: MetaCyc:1.14.21.2-RXN definition_reference: EC:1.14.21.2 term: (S)-coclaurine-N-methyltransferase activity goid: GO:0030794 definition: Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine. definition_reference: EC:2.1.1.140 term: (S)-methylmalonyl-CoA hydrolase activity goid: GO:0047511 definition: Catalysis of the reaction: (S)-methylmalonyl-CoA + H2O = methylmalonate + CoA. definition_reference: MetaCyc:(S)-METHYLMALONYL-COA-HYDROLASE-RXN definition_reference: EC:3.1.2.17 term: (S)-N-acetyl-1-phenylethylamine hydrolase activity goid: GO:0050536 definition: Catalysis of the reaction: N-acetylphenylethylamine + H2O = phenylethylamine + acetate. definition_reference: MetaCyc:3.5.1.85-RXN definition_reference: EC:3.5.1.85 term: (S)-norcoclaurine synthase activity goid: GO:0050474 definition: Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O. definition_reference: EC:4.2.1.78 term: (S)-norlaudanosoline synthase activity goid: GO:0050475 definition: Catalysis of the reaction: 2-(3,4-dihydroxyphenyl)ethylamine + 3,4-dihydroxyphenylacetaldehyde = (S)-norlaudanosoline + H2O. definition_reference: MetaCyc:(S)-NORLAUDANOSOLINE-SYNTHASE-RXN term: (S)-scoulerine 9-O-methyltransferase activity goid: GO:0030777 definition: Catalysis of the reaction: S-adenosyl-L-methionine + (S)-scoulerine = S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine. definition_reference: EC:2.1.1.117 term: (S)-stylopine synthase activity goid: GO:0047052 definition: Catalysis of the reaction: O2 + NADPH + S-cheilanthifoline = 2 H2O + NADP+ + S-stylopine. definition_reference: MetaCyc:1.1.3.32-RXN definition_reference: EC:1.14.21.1 term: (S)-tetrahydroprotoberberine N-methyltransferase activity goid: GO:0030782 definition: Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine. definition_reference: EC:2.1.1.122 term: (S)-usnate reductase activity goid: GO:0046998 definition: Catalysis of the reaction: L-usnic acid + NADH + H+ = NAD+ + 2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methyl-phenyl)-3-hydroxy-6-methyl-cyclohexa-2,4-dienone. definition_reference: MetaCyc:1.1.1.199-RXN definition_reference: EC:1.1.1.199 term: (S,S)-butanediol dehydrogenase activity goid: GO:0047512 definition: Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD+ = acetoin + NADH + H+. definition_reference: MetaCyc:(S,S)-BUTANEDIOL-DEHYDROGENASE-RXN definition_reference: EC:1.1.1.76 term: 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane catabolism goid: GO:0042188 definition: The breakdown into simpler components of 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide. definition_reference: GO:jl term: 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane metabolism goid: GO:0018977 definition: The chemical reactions and physical changes involving 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide. definition_reference: GO:jl term: 1,1,2-trichloroethylene reductive dehalogenase activity goid: GO:0050697 definition: Catalysis of the reaction: trichloroethylene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene. definition_reference: UM-BBD_enzymeID:e0271 definition_reference: MetaCyc:TCEREDCHLOR-RXN term: 1,1-dichloro-2,2-bis(4'-chlorophenyl)ethane dehydrochlorinase activity goid: GO:0018829 definition: Catalysis of the reaction: 1,1-dichloro-2,2-bis(4'-chlorophenyl)ethane (DDD) = HCl + 1-chloro-2,2-bis(4'-chlorophenyl)ethylene (DDMU). definition_reference: UM-BBD_enzymeID:e0351 term: 1,1-dichloro-2,2-bis(4'-chlorophenyl)ethylene dehalogenase activity goid: GO:0018702 definition: Catalysis of the reaction: 1,1-dichloro-2,2-bis(4'-chlorophenyl)ethylene (DDE) + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4'-chlorophenyl)ethylene (DDMU). definition_reference: UM-BBD_enzymeID:e0312 term: 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethylene 1,2-dioxygenase activity goid: GO:0018559 definition: Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4'-chlorophenyl)ethylene + O2 = 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate. definition_reference: UM-BBD_enzymeID:e0313 term: 1,2,3-tribromopropane metabolism goid: GO:0018976 definition: The chemical reactions and physical changes involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture. definition_reference: GO:jl term: 1,2,4-trichlorobenzene metabolism goid: GO:0018911 definition: The chemical reactions and physical changes involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides. definition_reference: http://www.speclab.com/compound/c120821.htm term: 1,2-alpha-L-fucosidase activity goid: GO:0047513 definition: Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside. definition_reference: MetaCyc:1,2-ALPHA-L-FUCOSIDASE-RXN definition_reference: EC:3.2.1.63 term: 1,2-beta-fructan 1F-fructosyltransferase activity goid: GO:0047207 definition: Catalysis of the reaction: (1,2-beta-D-fructosyl)(n) + (1,2-beta-D-fructosyl)(m) = (1,2-beta-D-fructosyl)(n+1) + (1,2-beta-D-fructosyl)(m-1). definition_reference: MetaCyc:2.4.1.100-RXN definition_reference: EC:2.4.1.100 term: 1,2-dehydroreticulinium reductase (NADPH) activity goid: GO:0047128 definition: Catalysis of the reaction: NADPH + 1,2-dehydroreticulinium = NADP+ + R-reticuline. definition_reference: MetaCyc:1.5.1.27-RXN definition_reference: EC:1.5.1.27 term: 1,2-diacylglycerol 3-beta-galactosyltransferase activity goid: GO:0046509 definition: Catalysis of the reaction: UDP-galactose + 1,2-diacylglycerol = UDP + 3-beta-D-galactosyl-1,2-diacylglycerol. definition_reference: EC:2.4.1.46 term: 1,2-diacylglycerol 3-glucosyltransferase activity goid: GO:0047228 definition: Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP. definition_reference: MetaCyc:2.4.1.157-RXN definition_reference: EC:2.4.1.157 term: 1,2-dichloroethane catabolism goid: GO:0019260 definition: The breakdown into simpler components of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride. definition_reference: GO:curators term: 1,2-dichloroethane metabolism goid: GO:0018899 definition: The chemical reactions and physical changes involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride. definition_reference: GO:jl term: 1,2-dichloroethene reductive dehalogenase activity goid: GO:0018705 definition: Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride. definition_reference: UM-BBD_enzymeID:e0272 term: 1,2-dihydrovomilenine reductase activity goid: GO:0050615 definition: Catalysis of the reaction: 17-O-acetylnorajmaline + NADP+ = 1,2-dihydrovomilenine + NADPH + H+. definition_reference: MetaCyc:1.3.1.73-RXN definition_reference: EC:1.3.1.73 term: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity goid: GO:0018521 definition: Catalysis of the reaction: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ = 3-methylcatechol + NADH + H+ + CO2. definition_reference: EC:1.3.1.68 term: 1,2-dihydroxy-phenanthrene glycosyltransferase activity goid: GO:0018718 definition: Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP. definition_reference: UM-BBD_enzymeID:e0378 term: 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity goid: GO:0018557 definition: Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid. definition_reference: UM-BBD_enzymeID:e0295 term: 1,2-dihydroxynaphthalene dioxygenase activity goid: GO:0018554 definition: Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached. definition_reference: UM-BBD_enzymeID:e0255 term: 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity goid: GO:0018566 definition: Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate. definition_reference: UM-BBD_enzymeID:e0250 term: 1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity goid: GO:0018777 definition: Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol). definition_reference: UM-BBD_enzymeID:e0361 term: 1,3-beta-D-glucan phosphorylase activity goid: GO:0047514 definition: Catalysis of the reaction: 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. definition_reference: MetaCyc:1,3-BETA-GLUCAN-PHOSPHORYLASE-RXN definition_reference: EC:2.4.1.97 term: 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity goid: GO:0050500 definition: Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1,3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate. definition_reference: MetaCyc:2.4.1.211-RXN definition_reference: EC:2.4.1.211 term: 1,3-beta-glucan synthase activity goid: GO:0003843 definition: Catalysis of the reaction: UDP-glucose + 1,3-beta-D-glucosyl(n) = UDP + 1,3-beta-D-glucosyl(n+1). definition_reference: EC:2.4.1.34 term: 1,3-beta-glucan synthase complex goid: GO:0000148 definition: The complex that catalyzes the transfer of a glucose moiety from UDP-glucose to a 1,3-beta-D-glucan chain. definition_reference: EC:2.4.1.34 term: 1,3-beta-glucanosyltransferase activity goid: GO:0042124 definition: Catalysis of the splitting and linkage of 1,3-beta-glucan molecules, resulting in 1,3-beta-glucan chain elongation. definition_reference: GO:jl definition_reference: PMID:10809732 term: 1,3-beta-oligoglucan phosphorylase activity goid: GO:0047515 definition: Catalysis of the reaction: 1,3-b-D-glucosyl(n) + phosphate = 1,3-b-D-glucosyl(n-1) + a-D-glucose 1-phosphate. definition_reference: MetaCyc:1,3-BETA-OLIGOGLUCAN-PHOSPHORYLASE-RXN definition_reference: EC:2.4.1.30 term: 1,3-dichloro-2-propanol biosynthesis goid: GO:0046309 definition: The formation from simpler components of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. definition_reference: GO:ai term: 1,3-dichloro-2-propanol catabolism goid: GO:0046310 definition: The breakdown into simpler components of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. definition_reference: GO:ai term: 1,3-dichloro-2-propanol metabolism goid: GO:0018902 definition: The chemical reactions and physical changes involving 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. DCP is used as a general solvent, as an intermediate in organic synthesis and in paints, varnishes, lacquers, water colors, binders and photographic lacquers. definition_reference: GO:jl definition_reference: UM-BBD:pathway definition_reference: http://umbbd.ahc.umn.edu/dcp/dcp_map.html term: 1,3-dichloropropene metabolism goid: GO:0018903 definition: The chemical reactions and physical changes involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes. definition_reference: UM-BBD:pathway definition_reference: http://umbbd.ahc.umn.edu/cpr/cpr_map.html term: 1,3-propanediol dehydrogenase activity goid: GO:0047516 definition: Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+. definition_reference: MetaCyc:1,3-PROPANEDIOL-DEHYDROGENASE-RXN definition_reference: EC:1.1.1.202 term: 1,4-alpha-glucan branching enzyme activity goid: GO:0003844 definition: Catalysis of the transfer of a segment of a 1,4-a-D-glucan chain to a primary hydroxyl group in a similar glucan chain. definition_reference: EC:2.4.1.18 term: 1,4-beta-D-xylan synthase activity goid: GO:0047517 definition: Catalysis of the reaction: UDP-D-xylose + 1,4-b-D-xylan(n) = UDP + 1,4-b-D-xylan(n+1). definition_reference: MetaCyc:1,4-BETA-D-XYLAN-SYNTHASE-RXN definition_reference: EC:2.4.2.24 term: 1,4-dichlorobenzene catabolism goid: GO:0019261 definition: The breakdown into simpler components of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. definition_reference: GO:ai term: 1,4-dichlorobenzene metabolism goid: GO:0018912 definition: The chemical reactions and physical changes involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs. definition_reference: http://www.speclab.com/compound/c106467.htm term: 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity goid: GO:0046428 definition: Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + pyrophosphate + CO2. definition_reference: MetaCyc:DMK-RXN term: 1,4-lactonase activity goid: GO:0050490 definition: Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid. definition_reference: MetaCyc:1,4-LACTONASE-RXN definition_reference: EC:3.1.1.25 term: 1,5-anhydro-D-fructose reductase activity goid: GO:0050571 definition: Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP+ = 1,5-anhydro-D-fructose + NADPH + H+. definition_reference: MetaCyc:1.1.1.263-RXN definition_reference: EC:1.1.1.263 term: 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity goid: GO:0018512 definition: Catalysis of the reaction: 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH + H+. definition_reference: EC:1.3.1.59 term: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity goid: GO:0047116 definition: Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol. definition_reference: MetaCyc:1.3.1.25-RXN definition_reference: EC:1.3.1.25 term: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity goid: GO:0003949 definition: Catalysis of the reaction: N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide = N-(5'-phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide. definition_reference: EC:5.3.1.16 term: 1-acylglycerol-3-phosphate O-acyltransferase activity goid: GO:0003841 definition: Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. definition_reference: EC:2.3.1.51 term: 1-acylglycerophosphocholine O-acyltransferase activity goid: GO:0047184 definition: Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + coenzyme A. definition_reference: MetaCyc:2.3.1.23-RXN definition_reference: EC:2.3.1.23 term: 1-alkenyl-2-acylglycerol choline phosphotransferase activity goid: GO:0047359 definition: Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP. definition_reference: MetaCyc:2.7.8.22-RXN definition_reference: EC:2.7.8.22 term: 1-alkenylglycerophosphocholine O-acyltransferase activity goid: GO:0047159 definition: Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + coenzyme A. definition_reference: MetaCyc:2.3.1.104-RXN definition_reference: EC:2.3.1.104 term: 1-alkenylglycerophosphoethanolamine O-acyltransferase activity goid: GO:0047166 definition: Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + coenzyme A. definition_reference: MetaCyc:2.3.1.121-RXN definition_reference: EC:2.3.1.121 term: 1-alkyl-2-acetylglycerol O-acyltransferase activity goid: GO:0047167 definition: Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + coenzyme A. definition_reference: MetaCyc:2.3.1.125-RXN definition_reference: EC:2.3.1.125 term: 1-alkyl-2-acetylglycerophosphocholine esterase activity goid: GO:0003847 definition: Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate. definition_reference: EC:3.1.1.47 term: 1-alkylglycerophosphocholine O-acetyltransferase activity goid: GO:0047192 definition: Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + coenzyme A. definition_reference: MetaCyc:2.3.1.67-RXN definition_reference: EC:2.3.1.67 term: 1-alkylglycerophosphocholine O-acyltransferase activity goid: GO:0047191 definition: Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + coenzyme A. definition_reference: MetaCyc:2.3.1.63-RXN definition_reference: EC:2.3.1.63 term: 1-aminocyclopropane-1-carboxylate biosynthesis goid: GO:0042218 definition: The formation from simpler components of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene, a fruit-ripening hormone in plants. definition_reference: GO:curators term: 1-aminocyclopropane-1-carboxylate catabolism goid: GO:0042217 definition: The breakdown into simpler components of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene, a fruit-ripening hormone in plants. definition_reference: GO:curators term: 1-aminocyclopropane-1-carboxylate deaminase activity goid: GO:0008660 definition: Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH3. definition_reference: EC:3.5.99.7 comment: Note that this function was formerly EC:4.1.99.4. term: 1-aminocyclopropane-1-carboxylate metabolism goid: GO:0018871 definition: The chemical reactions and physical changes involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene, a fruit-ripening hormone in plants. definition_reference: UM-BBD:pathway definition_reference: http://umbbd.ahc.umn.edu/acp/acp_map.html term: 1-aminocyclopropane-1-carboxylate oxidase activity goid: GO:0009815 definition: Catalysis of the reaction: ascorbate + 1-aminocyclopropane-1-carboxylate + O2 = 2 H2O + ethylene + L-dehydro-ascorbate + hydrocyanic acid + CO2. definition_reference: EC:1.14.17.4 definition_reference: MetaCyc:ETHYL-RXN term: 1-aminocyclopropane-1-carboxylate synthase activity goid: GO:0016847 definition: Catalysis of the reaction: S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine. definition_reference: EC:4.4.1.14 term: 1-chloro-2,2-bis(4'-chlorophenyl)ethane dehydrochlorinase activity goid: GO:0018827 definition: Catalysis of the reaction: 1-chloro-2,2-bis(4'-chlorophenyl)ethane (DDMS) = HCl + unsym-bis(4'-chlorophenyl)ethylene (DDNU). definition_reference: UM-BBD_enzymeID:e0353 term: 1-chloro-2,2-bis(4'-chlorophenyl)ethane dehydrogenase activity goid: GO:0018497 definition: Catalysis of the reaction: 1-chloro-2,2-bis(4'-chlorophenyl)ethylene (DDMU) + 2 H+ + 2 e- = 1-chloro-2,2-bis(4'-chlorophenyl)ethane (DDMS). definition_reference: UM-BBD_enzymeID:e0352 term: 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity goid: GO:0030604 definition: Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis. definition_reference: EC:1.1.1.267 definition_reference: Sanger:mb term: 1-deoxy-D-xylulose-5-phosphate synthase activity goid: GO:0008661 definition: Catalysis of the reaction: pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. definition_reference: EC:2.2.1.7 term: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase activity goid: GO:0046429 definition: Catalysis of the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. definition_reference: PMID:11752431 term: 1-hydroxy-2-naphthaldehyde dehydrogenase activity goid: GO:0018472 definition: Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate. definition_reference: UM-BBD_enzymeID:e0328 term: 1-hydroxy-2-naphthoate 1,2-dioxygenase activity goid: GO:0018582 definition: Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate. definition_reference: EC:1.13.11.38 term: 1-hydroxy-2-naphthoate hydroxylase activity goid: GO:0018637 definition: Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene. definition_reference: UM-BBD_enzymeID:e0332 term: 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity goid: GO:0018646 definition: Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate. definition_reference: UM-BBD_enzymeID:e0464 term: 1-indanone dioxygenase activity goid: GO:0018608 definition: Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone. definition_reference: UM-BBD_enzymeID:e0296 term: 1-indanone monooxygenase activity goid: GO:0018607 definition: Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin. definition_reference: UM-BBD_enzymeID:e0298 term: 1-methyladenosine nucleosidase activity goid: GO:0047518 definition: Catalysis of the reaction: 1-methyladenosine + H2O = 1-methyladenine + D-ribose. definition_reference: MetaCyc:1-METHYLADENOSINE-NUCLEOSIDASE-RXN definition_reference: EC:3.2.2.13 term: 1-oxa-2-oxocycloheptane lactonase activity goid: GO:0018731 definition: Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate. definition_reference: UM-BBD_enzymeID:e0167 term: 1-phenanthrol glycosyltransferase activity goid: GO:0018716 definition: Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O. definition_reference: UM-BBD_enzymeID:e0356 term: 1-phenanthrol methyltransferase activity goid: GO:0018707 definition: Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene. definition_reference: UM-BBD_enzymeID:e0336 term: 1-phenanthrol sulfotransferase activity goid: GO:0018722 definition: Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate. definition_reference: UM-BBD_enzymeID:e0373 term: 1-phenylethanol dehydrogenase activity goid: GO:0018449 definition: Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2. definition_reference: UM-BBD_enzymeID:e0210 term: 1-phosphatidylinositol 3-kinase goid: GO:0004429 definition: OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate. definition_reference: GO:mah definition_reference: EC:2.7.1.137 comment: To update annotations, consider the molecular function term 'phosphatidylinositol 3-kinase activity ; GO:0016303'. term: 1-phosphatidylinositol 4-kinase activity goid: GO:0004430 definition: Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate. definition_reference: MEDLINE:98431659 definition_reference: EC:2.7.1.67 term: 1-phosphatidylinositol-3-phosphate 5-kinase activity goid: GO:0000285 definition: Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate. definition_reference: EC:2.7.1.150 term: 1-phosphatidylinositol-4-phosphate 5-kinase activity goid: GO:0016308 definition: Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. definition_reference: EC:2.7.1.68 term: 1-phosphatidylinositol-4-phosphate kinase goid: GO:0004431 definition: OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. definition_reference: GO:curators definition_reference: EC:2.7.1.68 comment: To update annotations, consider the molecular function term '1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308'. term: 1-phosphatidylinositol-4-phosphate kinase, class IA goid: GO:0004432 definition: OBSOLETE. A class I PI3K activated by tyrosine phosphorylation events. definition_reference: MEDLINE:20504572 comment: This term was made obsolete because it is not a valid molecular function. To update annotations, consider the molecular function term '1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308'. term: 1-phosphatidylinositol-4-phosphate kinase, class IB goid: GO:0004433 definition: OBSOLETE. A class I PI3K activated via heterotrimeric G-proteins. definition_reference: MEDLINE:20504572 comment: This term was made obsolete because it is not a valid molecular function. To update annotations, consider the molecular function term '1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308'. term: 1-phosphatidylinositol-5-phosphate 4-kinase activity goid: GO:0016309 definition: Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. definition_reference: EC:2.7.1.149 term: 1-phosphatidylinositol-5-phosphate kinase goid: GO:0008438 definition: OBSOLETE. Catalysis of the reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide. definition_reference: EC:2.7.1.143 comment: This term was made obsolete because it is a redundant grouping term with only one child. It is also incorrectly defined and had an incorrect EC dbxref. To update annotations, consider the molecular function term '1-phosphatidylinositol-5-phosphate 4-kinase activity ; GO:0016309'. term: 1-phosphofructokinase activity goid: GO:0008662 definition: Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate. definition_reference: EC:2.7.1.56 term: 1-pyrroline-4-hydroxy-2-carboxylate deaminase activity goid: GO:0047425 definition: Catalysis of the reaction: H2O + 1-pyrroline-4-hydroxy-2-carboxylate = NH3 + 2,5-dioxopentanoate. definition_reference: MetaCyc:3.5.4.22-RXN definition_reference: EC:3.5.4.22 term: 1-pyrroline-5-carboxylate dehydrogenase activity goid: GO:0003842 definition: Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H+. definition_reference: EC:1.5.1.12 term: 10-deacetylbaccatin III 10-O-acetyltransferase activity goid: GO:0050643 definition: Catalysis of the reaction: acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III. definition_reference: MetaCyc:2.3.1.167-RXN definition_reference: EC:2.3.1.167 term: 10-formyltetrahydrofolate biosynthesis goid: GO:0009257 definition: The formation from simpler components of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. definition_reference: GO:ai term: 10-formyltetrahydrofolate catabolism goid: GO:0009258 definition: The breakdown into simpler components of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. definition_reference: GO:ai term: 10-formyltetrahydrofolate metabolism goid: GO:0009256 definition: The chemical reactions and physical changes involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. definition_reference: GO:ai term: 10-hydroxydihydrosanguinarine 10-O-methyltransferase activity goid: GO:0030779 definition: Catalysis of the reaction: S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-homocysteine + dihydrochelirubine. definition_reference: EC:2.1.1.119 term: 10-hydroxytaxane O-acetyltransferase activity goid: GO:0050639 definition: Catalysis of the reaction: acetyl-CoA + 10-desacetyltaxuyunnanin C = CoA + taxuyunnanin C. definition_reference: MetaCyc:2.3.1.163-RXN definition_reference: EC:2.3.1.163 term: 11-beta-hydroxysteroid dehydrogenase activity goid: GO:0003845 definition: Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+. definition_reference: EC:1.1.1.146 term: 11-cis retinal binding goid: GO:0005502 definition: Interacting selectively with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. definition_reference: http://cancerweb.ncl.ac.uk/omd/index.html term: 11-cis-retinyl-palmitate hydrolase activity goid: GO:0047520 definition: Catalysis of the reaction: 11-cis-retinyl palmitate + H2O = 11-cis-retinol + palmitate. definition_reference: MetaCyc:11-CIS-RETINYL-PALMITATE-HYDROLASE-RXN definition_reference: EC:3.1.1.63 term: 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity goid: GO:0030766 definition: Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline. definition_reference: EC:2.1.1.94 term: 12-alpha-hydroxysteroid dehydrogenase activity goid: GO:0047013 definition: Catalysis of the reaction: NADP+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate = NADPH + 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate. definition_reference: MetaCyc:1.1.1.176-RXN definition_reference: EC:1.1.1.176 term: 12-beta-hydroxysteroid dehydrogenase activity goid: GO:0047521 definition: Catalysis of the reaction: 3-alpha,7-alpha,12-beta-trihydroxy-5-beta-cholanate + NADP+ = 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate + NADPH + H+. definition_reference: MetaCyc:12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN definition_reference: EC:1.1.1.238 term: 12-hydroxydihydrochelirubine 12-O-methyltransferase activity goid: GO:0030780 definition: Catalysis of the reaction: S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine = S-adenosyl-L-homocysteine + dihydromacarpine. definition_reference: EC:2.1.1.120 term: 12-oxophytodienoate reductase activity goid: GO:0016629 definition: Catalysis of the reaction: 8-((1R,2R)-3-oxo-2-((Z)-pent-2-enyl)cyclopentyl)octanoate + NADP+ = (15Z)-12-oxophyto-10,15-dienoate + NADPH. definition_reference: EC:1.3.1.42 term: 13-hydroxydocosanoate 13-beta-glucosyltransferase activity goid: GO:0047229 definition: Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP. definition_reference: MetaCyc:2.4.1.158-RXN definition_reference: EC:2.4.1.158 term: 13-hydroxylupinine O-tigloyltransferase activity goid: GO:0047203 definition: Catalysis of the reaction: 13-hydroxylupinine + (E)-2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyl)oxylupinine + coenzyme A. definition_reference: MetaCyc:2.3.1.93-RXN definition_reference: EC:2.3.1.93 term: 15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity goid: GO:0050617 definition: Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin. definition_reference: MetaCyc:1.3.7.2-RXN definition_reference: EC:1.3.7.2 term: 15-hydroxyicosatetraenoate dehydrogenase activity goid: GO:0047034 definition: Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate. definition_reference: MetaCyc:1.1.1.232-RXN definition_reference: EC:1.1.1.232 term: 15-hydroxyprostaglandin dehydrogenase (NAD) activity goid: GO:0016404 definition: Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+. definition_reference: EC:1.1.1.141 term: 15-hydroxyprostaglandin dehydrogenase (NADP) activity goid: GO:0047021 definition: Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate = NADPH + (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate. definition_reference: MetaCyc:1.1.1.197-RXN definition_reference: EC:1.1.1.197 term: 15-hydroxyprostaglandin-D dehydrogenase (NADP) activity goid: GO:0047020 definition: Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate. definition_reference: MetaCyc:1.1.1.196-RXN definition_reference: EC:1.1.1.196 term: 15-hydroxyprostaglandin-I dehydrogenase (NADP) activity goid: GO:0047033 definition: Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate = NADPH + (5Z,13E)-6,9-alpha-epoxy-11-alpha-hydroxy-15-oxoprosta-5,13-dienoate. definition_reference: MetaCyc:1.1.1.231-RXN definition_reference: EC:1.1.1.231 term: 15-oxoprostaglandin 13-oxidase activity goid: GO:0047522 definition: Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+. definition_reference: MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN definition_reference: EC:1.3.1.48 term: 16-alpha-hydroxyprogesterone dehydratase activity goid: GO:0047455 definition: Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone. definition_reference: MetaCyc:4.2.1.98-RXN definition_reference: EC:4.2.1.98 term: 16-alpha-hydroxysteroid dehydrogenase activity goid: GO:0047005 definition: Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + 16-oxosteroid. definition_reference: MetaCyc:1.1.1.147-RXN definition_reference: EC:1.1.1.147